I just happen to be used to read that part of the en.wiki article over and over lately... Still, if we -- I will repeat -- mistakenly try to write on the space where we are not supposed to, will some sort of protection prevent us from doing that? If not, could such actions prove fatal for the Wii Remote?
That were the questions. Now I took a look on the wiibrew article, and it kind of confirms what I am afraid of.
Remember to set bit 2 (0x04) on the first byte of the Output Report, otherwise you'll overwrite EEPROM memory!
http://wiibrew.org/wiki/Wiimote#Control_Registers