The Mobi-pad project, Wiimote Connect (Thex) & Java IWB (UJS) have all proved it is possible. Java IWB connects with the wiimote through the API and Ujs advises me that this won't allow connection with .net frameworks apps (best programming framework for Windows). However Ujs has proved that the same code can be used for all stacks.
I'm blindly throwing a cool Idea out there, I don't even know what a API or Library for Bluetooth looks like? Ujs would be the best person to help you as he sucesfully integrated a Bluetooth connection utility in his IWB application.
Really Thex's Wiimote Connect just needs to be extended to include support for Bluesoleil & Widcomm.